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In humans, probiotics supplementation seems to decrease values of metabolic parameters and leads to the reducing of the weight gain in obese adults (175) (Table 7)

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Tumour redox state, hypoxia, and acidosis imaging Tumour microenvironmental characteristics such as hypoxia, altered redox balance, and extracellular acidosis have emerged as central determinants of tumour aggressiveness, metastatic potential, and therapeutic resistance (181, 182)